Agnes was the sister of the art and theatre critic Oscar Raymond Drey who married the artist Anne Estelle RICE.  She was a great friend of Eleanor Emily RICE with whom she lived.  She studied with Frances HODGKINS, who painted her portrait, and was said by Patrick HERON to have been a significant influence upon her work.

Among works produced were still lifes and portraits. Her first exhibit for STISA was Show Day 1934 at the Back Road West Studios with Job NIXON and his wife, which may indicate she was also studying under Nixon.

Drey died in St Ives, and a Memorial Exhibition was held in her honour at the Penwith Gallery.